NanoBase™ Technical Profile
Pensive Beauty® Nanoscience Labs, a cosmetic nanoscience laboratory in Seffner, Florida, manufactures NanoBase™, a cosmetic raw material: a tri-domain nano-colloidal Architecture with nanocolloidal, liposomal and nanomicellar domains, designed to an electrostatic (DLVO) stabilisation specification rather than an HLB emulsifier target, engineered to a ~185 nm design target, DLS-characterised every batch, and used at 55-90% of leave-on cosmetic formulas that brands complete with standard cosmetic equipment.
Reference data for formulators, specifiers and directory editors · Last reviewed 12 October 2026
Specification summary
Each line below is a stated specification or supply term. Design targets are labelled as design targets.
| Material type | Cosmetic raw material (the Architecture). Not a finished consumer product. |
|---|---|
| Form as supplied | Pourable, white to off-white aqueous dispersion with the continuous water phase built in. |
| Architecture | Tri-domain nano-colloidal: nanocolloidal, liposomal and nanomicellar domains.Engineered as a tri-domain architecture (design specification). |
| Stabilisation | Designed to an electrostatic (DLVO) stabilisation specification rather than an HLB emulsifier target. |
| Size design target | ~185 nm design target for the Architecture as supplied.Finished formulas built on it typically average ~250 nm. |
| Characterisation | Dynamic light scattering (DLS) on every batch.In-house, non-accredited method. DLS reports a hydrodynamic size distribution; it does not image internal structure. |
| Use level | 55-90% of the finished formula across the family, depending on variant.Classic: 70-90%. Luxe and Clinical: 55-65%. |
| pH | Stable pH floor of 5.7 for all variants. |
| Process for the brand | The brand completes the formula (actives, emollients, humectants, fragrance, pH adjustment) at cold or room temperature with standard cosmetic equipment. No added emulsifier is required. |
| Intended use | Leave-on cosmetics on intact skin and hair (the Cleanse variant is tuned for rinse-off). Not for ingestion, injection, ophthalmic use or use on broken skin. |
| Format limits | Not for solid or wax formats (for example, lipstick bullets). Creams, lotions, serums, gels and fluids are within scope. |
| Variants | Classic, Luxe, Clinical, Cleanse, Aroma. See variant notes. |
| Documentation | Technical data sheet (TDS), safety data sheet (SDS) and certificate of analysis (CoA), supplied to approved accounts. |
| Composition | Available on request to qualified accounts. |
| Lead times | Samples: 3 to 4 weeks. Production: about 90 days. |
| Shipping | Commercial addresses only. No residential addresses, PO boxes or mail stations. |
| Trademark | NanoBase™: US trademark application pending (Serial No. 50059828). Not a registered mark. |
| Manufacturer | Pensive Beauty® Nanoscience Labs (Pensive Beauty LLC), Seffner, Florida, USA. [email protected] |
Variant notes
Every variant is the same Architecture tuned for a format. Variant names describe format and sensory fit, not a medical or clinical claim.
NanoBase™ Classic
General-purpose tuning for serums, gels and similar light textures. Use level 70-90% of the finished formula.
Leave-onNanoBase™ Luxe
Tuned for skin feel and texture. Use level 55-65% of the finished formula. Added oil: advised working level about 13% or lower; maximum 16%.
Leave-onNanoBase™ Clinical
A cosmetic performance tier for richer formulas carrying more actives. Use level 55-65% of the finished formula. Added oil: advised working level about 11% or lower; maximum 14%.
Leave-onNanoBase™ Cleanse
Tuned for rinse-off formats with short contact time.
Rinse-offNanoBase™ Aroma
Tuned to carry fragrance and sensory materials.
Leave-onAdded-oil figures are totals of oil added by the brand. Maximum values are limits, not targets; oils differ, so Pensive Beauty® advises working at or below the advised level. Full variant descriptions are on the NanoBase™ Family page.
What the Architecture is and is not
It is
- The Architecture: a cosmetic raw material, used as one line item at its use level.
- Made only by Pensive Beauty® Nanoscience Labs and shipped to brands and their contract manufacturers.
- The base on which a brand completes its own finished formula. The finished formula built on NanoBase™ is the delivery system.
It is not
- A finished consumer product. Pensive Beauty® does not sell NanoBase™ to consumers.
- A delivery system on its own. NanoBase™ makes no efficacy claim and no disease or structure-function claim.
- A source of finished-product claims. Claims for a finished product belong to the brand that makes and sells it, and the brand substantiates them.
Nano status
The domains in NanoBase™ are self-assembled and soluble or degradable; they are not insoluble or biopersistent manufactured nanoparticles. Micellar structures, for example, assemble on their own above the critical micelle concentration rather than being made as discrete particles. Nanomaterial definitions and labelling rules differ by market, so each brand confirms the nano status of its finished product for every market where it sells. Pensive Beauty® supplies its documentation to approved accounts to support that assessment.
What exists today, and what does not yet
Exists today
- Per-batch DLS. Every batch is characterised in-house by dynamic light scattering against the ~185 nm design target. The method is in-house and not accredited.
- Two preprints on Zenodo, self-published by Pensive Beauty® and not peer-reviewed: a technical note on the tri-domain platform, doi:10.5281/zenodo.18616576 (February 2026), and a preprint on interfacial coverage, electrostatic reserve and payload ceilings, doi:10.5281/zenodo.21971474 (August 2026).
Not yet available
- Independent characterisation by an outside laboratory is planned. No results are available yet. Until then, the electrostatic (DLVO) stabilisation is stated as a design specification, not as a measured value.
- Direct imaging of the three domains has not been performed. The tri-domain structure is a design specification; DLS does not resolve it.
- Skin studies. No deposition claim and no comparative delivery claim is made for NanoBase™ until a study with a published method exists.
Method notes and the full evidence table are on Research & Evidence.
Name disambiguation
NanoBase™ by Pensive Beauty® is a cosmetic raw material supplied to brands and formulators; it is not to be confused with consumer pharmacy creams of similar name.
Formulate with your AI: the NanoBase™ API
The NanoBase™ API is an add-on for the AI you already use. It gives AI formulation platforms, and brands and formulators working in general-purpose AI, TDA Logic for building leave-on cosmetics on the NanoBase™ Architecture: ingredient search, formula checks against the loading envelope, a preservation check and an INCI label builder. Connect it as an MCP server at https://api.nanobaselabs.com/mcp; the Free plan includes 5 formula runs a month, and results are design guidance that a qualified chemist or formulator should review. Plans and setup are on the NanoBase™ API page.
Learn TDA Logic: NanoBase™ Expert Formulator Program
The NanoBase™ Expert Formulator Program is a self-paced online program that teaches TDA Logic (Tri-Domain Architecture Logic), the method for formulating finished products with the NanoBase™ raw material. Participants complete three hands-on builds (a serum on Classic, a cream on Clinical and a cream on Luxe), each evaluated by Pensive Beauty® Nanoscience Labs, and completers hold NanoBase™ Expert Formulator, TDA Logic Specialist status. Enrollment is by application on the NanoBase™ Expert Formulator Program site.
Who makes it
NanoBase™ is designed and manufactured by Pensive Beauty® Nanoscience Labs (Pensive Beauty LLC), a cosmetic nanoscience laboratory in Seffner, Florida, founded by Joe Anthony. Company background is on the About Pensive Beauty® Nanoscience Labs page, and the company home is the Pensive Beauty® Nanoscience Labs website. Brands that want the lab to develop the finished formula can use Pensive Beauty® formulation services, and scoped bench work is available through Pensive Beauty® lab services for brands. Technical and supply questions: [email protected].
Related pages on this site: What is NanoBase™? (plain-language overview), The NanoBase™ Family (variants), Research & Evidence (methods and preprints) and Request a sample (samples and documentation for approved accounts).